Is Cannabinoid Hyperemesis Syndrome (CHS) caused by an accumulation of anything in the body?
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Things that could resolve this Yes

  • Cannabinoids binding to receptors and not being released

  • Metabolites

  • Gut Microbiota

  • Containments (unlikely)

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#Cannabinoid Hyperemesis Syndrome
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What about changes in hormone levels, maybe not an accumulation, but a lack of a certain hormone?

@EstMtz If the lack of hormones causes CHS and the lack of hormones are caused by a build up or accumulation, then Yes.

What about other non CB receptors becoming upregulated or downregulated? For example, a non-CB receptor that is downregulated and now no longer functions as normal?

@EstMtz If CBD binds to TRPV1 receptors and lingers around - causing CHS this resolves Yes. If THCV binds and quickly dissociates and doesn't hang around, but the interaction causes a up/down regulation and that causes CHS this resolve No.

If both of these things contribute to CHS then it resolves Yes.

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